This book provides health care workers and mangers with information and practical guidance relating to antiretroviral therapies (ART). It also considers wider care and treatment issues such as; opportunistic infections, the integration of ART with antenatal and midwifery services, the particular needs of children and young people, support relating to nutrition, spiritual needs, psycho-social and economic issues. In addition, the need for community level support to help with adherence to treatment and address stigma and discrimination are also considered, as is end-of-life care for people whose disease does not respond to treatment