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Antimalarial drug quality in the most severely malarious parts of Africa - a six country study

BATE, Roger
COTICELLI, Philip
TREN, Richard
ATTARAN, Amir
May 2008

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This article describes research conducted on a range of antimalarial drugs, procured from private pharmacies in urban and peri-urban areas in the major cities of six African countries which were subjected to semi-quantitative thin-layer chromatography (TLC) and dissolution testing to measure active pharmaceutical ingredient content against internationally acceptable standards

Spatial patterns of leprosy in an urban area of central Brazil

MARTELLI, C M T
et al
1995

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Reported is the spatial variation of leprosy in an urban area of Brazil and its correlation with socioeconomic indicators. From November 1991 to October 1992 a total of 752 newly diagnosed leprosy patients who were attending all outpatient clinics in Golania city, central Brazil, were indentified. A database of leprosy cases was set up linking patients' addresses to 64 urban districts. Leprosy cases were detected in 86 of the districts and three risk strata were identified. The highest risk area for leprosy was in the outskirts of the city and detection rates increased on moving from more developed to poorer areas. The risk of detecting leprosy cases was 5.3-fold greater (95CL: 3.8-7.4) in the outskirst of the town than in the central zone.
Discussed are the methodological issues related to leprosy case ascertainment, completeness and reliability of information, and the interpretation of the spatial distribution of leprosy per unti area. High lighted also are the lack of deprosy control activities in primary health care units and the usefulness of geographical analysis in planning health services.

Case-control study of intrapartum care, cerebral palsy, and perinatal death

Gaffney, Geraldine
1994

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There is an association between quality of intrapartum care and death. The findings also suggest an association between suboptimal care and cerebral palsy, but this seems to have a role in only a small proportion of all cases of cerebral palsy. The contribution of adverse antenatal factors in the origin of cerebral palsy needs further study

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